There are 6,100 hospitals in the United States. The largest among them is New York-Presbyterian Weill Cornell Medical Center, with a bed count of 2,850. Wondering how many patients visit this hospital per year? Nearly 3.31 million according to official figures. On average, that’s over 9,000 patient visits per day! With such a high influx of patients, U.S. hospitals and other large multi-specialty practices are forced to manage a high volume of paperwork, including claim creation and maintaining documentation.
What’s worse? In 2024, 43.2% of physicians reported feeling burned out because they were spending around 13 hours on indirect patient care, including data entry and documentation, and 7.3 hours on administrative tasks like insurance form filling.
U.S. healthcare providers deserve the same level of care that they render to their patients. That’s why, since the 1970s, professional medical billing services for large healthcare practices have been available in the market with the goal of streamlining insurance billing and fast-tracking insurance claim submission.
Today, we will deep dive into the world of medical billing for large practices and understand how third-party billing companies have become a reliable revenue management partner for multi-specialty practices across the USA.
Medical Billing Challenges Faced by Large Healthcare Practices
We have already given you an overview of the tribulations that physicians and other healthcare staff face due to administrative workload. However, now, it is time to reveal the full picture. So, let’s discuss some of the most prominent medical billing challenges that large healthcare practices encounter.
Front-Desk Delays and Mistakes
The first operational challenge that large practices face in the medical billing process is patient eligibility verification and accurate data entry at the front desk or during patient intakes. This is because large practices have a high patient inflow, but due to high turnover in the healthcare industry, they, too, experience staff shortages.
So, at any given time, just two or three front-desk personnel are attending to patients, recording their demographic details, verifying their insurance plans and benefits, and redirecting them to the appropriate specialties and physicians. It not only increases patient wait times but also leads to hasty and erroneous data verification and entry, ultimately triggering claim denials.
High Claim Volume
As discussed before, a high inflow of patients directly translates to high claim volume. This complicates medical billing for large practices because physicians and their administrative staff spend hours every day sorting through logs and patient charts to file claims to various insurance payers and collect reimbursement for their services.
Complex Multi-Specialty Coding
Many large healthcare practices in the country integrate multiple specialties under one roof for comprehensive medical care. However, this complicates medical coding for in-house billers.
The reason is that every medical specialty has its own ICD-10 and CPT codes. Moreover, medical coding requires specificity, which is conveyed via two-digit modifiers. Many of these modifiers are also specialty or service-specific (e.g., anesthesia modifiers and surgical modifiers). In-house billers are often not well-versed in these nuances and tend to unbundle or upcode services, triggering payment denials and audits.
EHR Integration and Interoperability Gaps
Another medical billing challenge that large healthcare practices often complain about is working on three or four different Electronic Health Record (EHR) systems and ensuring data is synchronized across all for up-to-date record-keeping.
However, EHR integration requires specialized tech teams. And sometimes, after systems have been synced, technical glitches can hinder seamless integration, leading to a documentation mismatch and erroneous claim filing.
Unique Payer Rules and Policies
Typically, a large multi-speciality or multi-location healthcare practice in the USA has contracts with 35 to 82 different insurance payers. These include government (Medicare and Medicaid) as well as private payers. The problem is that every payer’s billing requirements and contract policies vary, making it extremely taxing for providers and their billing teams to remember the unique guidelines and ensure compliance.
Declining Reimbursement Rates
Perhaps this year’s biggest medical billing challenge for large healthcare practices is the decrease in reimbursement rates.
As per the 2026 Medicare Physician Fee Schedule, payment for physician services performed at a facility will be reduced by 7%. In fact, 39% of oncologists could face payment cuts of up to 20%. Simply speaking, large practices cannot afford to lose more revenue due to denials.
Medical Billing Best Practices for Large Practices
You must already be familiar with medical billing best practices, like upfront eligibility verification, precise coding, and detailed documentation, which can help you avoid payment delays and denials. So, we will refrain from repetition.
Instead, we will discuss a few medical billing solutions and strategies that large practices are capable of implementing to overcome the challenges discussed above.
Automating Workflows
The first medical billing solution that large healthcare practices must consider is workflow automation. From leveraging artificial intelligence (AI)-driven tools for fast and accurate front-desk eligibility checks to automated claim scrubbing, you should invest in billing and practice management software. The reason?
In a 2024 survey conducted by the American Medical Association, two-thirds of physicians, or 66%, reported using AI. Moreover, 57% of physicians using AI said that automation was reducing administrative burdens. So, by implementing AI and robotic process automation (RPA), practitioners and admin staff at large practices can accelerate clean claim submission and payment collection.
Regular Staff Training
Did you know that medical billing departments are considered the engines of large, multi-provider healthcare practices? This is because medical billing kick-starts the revenue cycle, propelling the practice forward towards financial growth and stability. So, if the staff makes mistakes here, in the engine room, it affects the entire practice’s headway.
That’s why we recommend continuous staff training for everyone involved in the medical billing process at large practices. For example, the front-desk staff should receive training in efficient eligibility verification and patient registration, coders should be given knowledge of the latest revisions in the coding systems, and billers should be mentored on claim scrubbing, documentation best practices, and denial management.
Outsourcing Billing and Practice Management
The ultimate best medical billing solution for large practices is outsourcing. Now, what do we mean by that? We believe that healthcare practices with high patient flows and claim volumes should partner with reliable medical billing companies, so that healthcare staff can focus on patients instead of paperwork.
The greatest benefit of outsourcing medical billing is that, along with revenue optimization, practices can utilize à la carte services, like patient support, provider credentialing, and audits for effective practice management.
5 Best Medical Billing Software for Large Practices
The U.S. healthcare landscape is competitive, forcing practices to strive for greater accuracy, compliance, financial stability, and patient satisfaction. But with so many goals to achieve and a staff that is either burned out or on the verge of quitting, practices must turn towards innovative solutions. These solutions are available in the form of medical billing software, especially designed for large healthcare practices.
So, let’s look at the top 5 medical billing software that can cater to the needs of multi-specialty practices.
1. AdvancedMD
AdvancedMD’s medical billing software is the best for 360-degree practice management. It gives you access to a range of features and add-ons, including patient scheduling, data analytics and reporting, medical coding, cloud-hosted medical billing, and integrated clearinghouse services.
Its easy-to-read built-in dashboards display daily updates, allowing you to track the financial performance of your large practice in real time. Moreover, with all data from different patients and providers on one centralized cloud platform, claims management becomes effective.
Since the early 2000s, AdvancedMD’s automated workflows and innovative tools, like claim scrubbers, have been helping private practices, especially large ones, achieve a 95%+ first-pass acceptance rate. No wonder it has become the go-to billing software for 65,000 practitioners across 14,000 practices.
Some of its medical billing solutions for large practices include:
- Patient engagement and mobile applications.
- Electronic health records.
- Credit card processing, automated reminders, and online payments.
- Full-service practice management with analytics and business intelligence.
2. CareCloud
CareCloud is another leading healthcare technology company that builds and provides medical billing software to large healthcare practices. It offers an all-in-one, enterprise-ready, cloud platform to large medical groups for streamlined practice and revenue cycle management. So, even if you are a multi-location healthcare group, the software will centralize all operations and ensure seamless data exchange across all systems. Healthcare providers can “coordinate care, improve efficiency, and operate as one connected network”.
Moreover, the software automates key steps of the medical billing process, such as coding, claims management, and denial prevention, to speed up clean claim submission and reimbursement collection.
That’s not all. CareCloud’s AI-powered clinical tools, like CirrusAI Notes, automatically generate summaries, simplifying documentation and supporting clinical decision-making.
To summarize, CareCloud’s innovative medical billing solutions for large practices include:
- Specialty-specific electronic health records.
- Telehealth and virtual care.
- AI-driven chatbots and digital check-ins.
- Automated reminders.
- Patient portals.
- Virtual assistant for administrative tasks.
- Payer contract analytics and financial forecasting.
3. DrChrono
The next medical billing software that we will recommend to large healthcare practices is DrChrono by EverHealth. DrChrono, founded in 2009, was the first EHR system to build a native app for iPhones and iPads. Moreover, it has been voted the #1 EHR by physicians and the #1 mobile EHR by Black Book.
This medical billing software focuses on increasing revenue collection and reducing back-office work. Its premium features include billing profile creation, real-time eligibility, good faith estimates, claim submission, denial resolutions, patient statements, and ICD-10, CPT, and DSM5 medical coding.
So, if you are considering DrChrono’s medical billing platform for your large healthcare practice, you are likely to unlock the following benefits:
- Speciality and location-based customization in EHR.
- Guided implementation and an intuitive interface.
- Admin-restricted access.
- Telemedicine integrated platform.
- Automated patient statements.
- Denials addressed within 48 hours.
- Intelligent electronic medical records (EMRs).
- Integrated lab and imaging order options to over 40,000 diagnostic labs.
- Medical speech-to-text charting.
- HIPAA-compliant, white-label-ready patient portal.
4. eClinicalWorks
If you want to transform your large multi-specialty practice with AI-powered revenue cycle management (RCM) solutions, then look no further than eClinicalWorks. The company has been developing cloud-based products and solutions for over 20 years. Due to its constant innovation, it has become a leader in healthcareIT. Want proof? Its technological solutions are trusted by 180,000 physicians and nurse practitioners and 850,000 medical professionals worldwide.
eClinicalWorks’ comprehensive AI-powered suite includes products like:
- Healow Genie (an automated patient call answering solution).
- Sunoh.ai (an automated medical scribe that converts patient-provider communication into clinical documentation).
- Image AI (manages inbound faxes, matches them to patients, and interprets their purpose).
- AI Assistant (the industry’s first conversational EHR).
Remember, more than 111,000 facilities around the world are already running on eClinicalWorks, so are you ready to incorporate its medical billing solutions into your large practice?
5. NextGen Healthcare
The last of the top 5 medical billing software that is suited to empower large healthcare practices is NextGen. It is an award-winning integrated EHR software that delivers the flexibility and convenience that providers and patients expect from a single platform. Ranked as the #1 EHR and practice management (PM) solution by Black Book, NextGen promises expedited claims, improved performance, A/R best practices, training and support, and organized billing processes.
Apart from its EHR, NextGen has built a powerful AI documentation tool, Ambient Assist, that automatically transcribes patient visits, generates structured SOAP notes, and suggests relevant ICD-10 codes and medications. But the biggest advantage of Ambient Assist is that these notes sync automatically into the NextGen Enterprise EHR patient chart, helping providers save up to 2.5 hours a day.
A few other medical billing solutions that NextGen provides to large healthcare practices or enterprises include:
- NextGen Mobile (a user-friendly, cloud-based platform for documenting care).
- NextGen Intelligent Agent (providers and staff use voice and text commands to interact with the EHR and direct tasks to specialized AI agents).
- NextGen Closed Loop Patient & Practice Experience (a comprehensive tool for patient engagement, care coordination, and health management).
MediBillMD’s Medical Billing Services for Large Practices
The harsh reality is that even with a fully functional in-house medical billing team and industry-best EHR and practice management software, large practices struggle with timely claim filing and denials. The reason is simple – a lack of expert supervision.
MediBillMD understands the unique medical billing challenges that multi-specialty healthcare practices face. That’s why its medical billing services for large practices are designed to be scalable, tackle high claim volumes, standardize workflows, and guarantee a 97% first-pass ratio. From specialty-specific coding to effective payer communication and process automation, MediBillMD’s experienced, skilled, and certified team can handle everything with ease.
So, if you would like to outsource medical billing services for your large healthcare practice, rest assured that MediBillMD fits the mold of an expert supervisor.
